noun
insanity
in-SAN-uh-tee/ɪnˈsænəti/
A severe disturbance of rational mental functioning.
The lawyer raises insanity as a defense during the trial.

Etymology
These pieces express a state of not being sound or healthy. English used the noun for seriously impaired mental functioning, then extended it to extreme folly or irrationality.
In context
that there was disaster ahead and they were having to prepare for some awful eventualities and Shackleton realized this would have produced mental strain which probably would have led to insanity
More examples
- The old hospital records describe her condition as insanity.
- The novel traces his gradual descent into insanity.
- He is found not guilty by reason of insanity.
Forms
insane adjective — Severely impaired in rational mental functioning.
Similar words
- madness
- Often sounds literary or emotional rather than formal or legal.
- psychosis
- Specifically describes impaired contact with reality, not legal responsibility.