noun
irritation
ir-ih-TAY-shuhn/ˌɪrɪˈteɪʃn/
An uncomfortable reaction to an unwanted stimulus.
The dust causes irritation that makes the person rub a reddened eye.

Etymology
The pieces name the action or result of provoking a response. English first used the noun for sores and swelling; its later emotional sense names impatient or angry excitement.
In context
irritation and frustration is another popular reason why people put their hands on their hips
More examples
- His irritation fades when she explains the delay.
- This soap causes skin irritation.
- Dust can cause irritation in your eyes.
- She handles life's small irritations with humor.
Forms
irritation · irritations
irritate verb — To cause annoyance or physical discomfort.
Similar words
- annoyance
- Emphasizes displeasure rather than soreness or other physical discomfort.
- soreness
- Specifically describes bodily pain or tenderness, not emotional annoyance.
- discomfort
- Covers general unease without necessarily suggesting a provoking stimulus.