DictionaryligationMolecular joining
noun

ligation

Joining molecular fragments, especially DNA, by forming a chemical bond.

DNA ligation joins two fragments by forming a chemical bond.

Etymology

Latin ligare means to bind or tie. Molecular biology applies that joining image to connecting fragments, especially DNA, through a chemical bond.

More examples

  • The researchers use ligation to insert the gene into a plasmid.
  • We compare several ligations to find the best reaction conditions.
  • Ligation of these RNA fragments requires a suitable enzyme.

Forms

ligation · ligations

ligate verb — Join molecular fragments by forming chemical bonds.

ligase noun — Enzyme that forms bonds between molecular fragments.

Similar words

joining
Broader term that does not necessarily involve chemical bonds.
bonding
Covers chemical bond formation generally, not specifically joining molecular fragments.