adjective / noun
utmost
UT-mohst/ˈʌtmoʊst/
The greatest possible degree, amount, or effort.
The climber places the flag at the mountain's utmost height.

Etymology
“Out” with a superlative ending originally described the farthest point or outermost limit. That spatial limit became a limit of degree: the greatest possible amount or importance.
In context
I say this call to action to you with the deepest sincerity and utmost gravity.
And of course, lowering child mortality is a matter of utmost importance from humanitarian aspects.