noun
vesicle
VES-ih-kul/ˈvesɪkl/
A small enclosed sac or cavity containing fluid or gas.
The tiny vesicle encloses clear fluid beneath a thin dome of skin.

Etymology
Latin vesicula meant a 'little blister,' a diminutive of the word for 'bladder.' That small, hollow container image underlies the anatomical name for a fluid-filled sac.
In context
… folds in a little to form the beginning of a channel and then pinches off to form a vesicle that holds the fluid.
More examples
- The rash includes several small vesicles filled with clear fluid.
- Each vesicle in this volcanic rock marks a trapped gas bubble.
- A thin membrane surrounds the vesicle inside the cell.
Forms
vesicle · vesicles
vesicular adjective — Relating to or resembling small sacs.