noun
exacerbation
ig-zas-er-BAY-shun/ɪɡˌzæsərˈbeɪʃn/
A worsening of a problem or medical condition.
The spreading floor damage marks an exacerbation of the leak's effects.

Etymology
The “harsh, bitter” base gave a verb meaning “irritate or provoke,” with ex- perhaps intensifying it. The noun carries that idea of aggravation into the worsening of an illness, problem, or situation.
In context
Whether COVID-19 is causing respiratory illness or exacerbation of other underlying conditions
More examples
- Delaying repairs risks an exacerbation of the housing crisis.
- He has several exacerbations of his condition each year.
- Air pollution can trigger an exacerbation of chronic lung disease.
Forms
exacerbation · exacerbations
exacerbate verb — To make a problem or condition worse.
Similar words
- worsening
- A more everyday term for a decline in condition.
- aggravation
- Often stresses an outside factor making an existing problem worse.
- flare-up
- Emphasizes a sudden episode rather than worsening in general.